A robust method for finely stratified familial studies with proband-based sampling

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A robust method for finely stratified familial studies with proband-based sampling.

This paper presents a robust method to conduct inference in finely stratified familial studies under proband-based sampling. We assume that the interest is in both the marginal effects of subject-specific covariates on a binary response and the familial aggregation of the response, as quantified by intrafamilial pairwise odds ratios. We adopt an estimating function for proband-based family stud...

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ژورنال

عنوان ژورنال: Biostatistics

سال: 2009

ISSN: 1465-4644,1468-4357

DOI: 10.1093/biostatistics/kxn043